Brushfield spots

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Brushfield spots seen in

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[A] Marfan syndrome
[B] Down syndrome
[C] Turnor syndrome
[D] Patau syndrome

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Brushfield spots located in

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[A] Skin
[B] Oral Mucosa
[C] Iris
[D] Upper Chest

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Brushfield spots are formed due to aggregation of 

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[A] Pigments
[B] Hydroxyapatite
[C] Calcium
[D] Connective tissue

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Krückmann-Wolfflin bodies

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Similar spots like Brushfield spots described by Krückmann and Wolfflin found in individuals without Down syndrome.

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Krückmann-Wolfflin bodies compared to Brushfield spots of trisomy 21

	Krückmann-Wolfflin bodies	Brushfield spots of trisomy 21
1	Found in individuals without Down syndrome.	Found in individuals with Down syndrome.
2	less well defined	More well defined
3	Fewer in number	More in number
4	More peripherally located in Iris	Peripherally located in Iris

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