Image Question-27
What is the diagnosis of Histopathology Image ?

What is the diagnosis of Histopathology Image ?
A. Corpora amylacea
B. Colloid Goitre
C. Thymoma
D. Oligodendroglioma
In shorts
- In normal thyroid gland or more commonly in hyperplastic conditions of thyroid gland such as nodular/multinodular goiter, adenomatoid goiter, or adenomatous hyperplasia, microscopically dilated thyroid follicles lined by cuboidal cells and filled with colloid may be seen.
- When colloid secretion increases in the small secondary follicles, their mass bulges into the follicular cavity and gives rise to a “Sanderson Polster” seen at one pole along the follicular wall of enlarged and dilated follicles.
- These dilated follicles are usually 2–3 times larger than the surrounding follicles
- Sanderson’s polster is composed mainly of small follicles lined by cuboidal cells
What is ‘Sanderson Polster’ ?

Sanderson polsters
When colloid secretion increases in the small secondary follicles, their mass bulges into the follicular cavity and gives rise to a “Sanderson Polster” seen at one pole along the follicular wall of enlarged and dilated follicles.